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Antidepressants for pain management

From 1966 to 1997, studies in the United States tested certain commonly-prescribed antidepressant medication to establish if they could be used to treat pain, especially pain which was recurring or frequent.

Forms of pain tested

This type of pain relates to persistent headaches, high levels of nerve sensitivity associated with diabetes, fibromyalgia – a common condition causing pain in bones, muscles and joints – and other forms of mixed-chronic pain.

Help for pain

Antidepressants were found reliably helpful to treat mixed chronic-pain.  However, results were uncertain regarding their success in treating migraines, tension headaches, fibromyalgia and pain linked to diabetes.  But, patients with these pain conditions who are not achieving any success with other medications, or have bad side-effects from them, should try antidepressants to see if they may relieve pain in their specific case.

View the original chronic pain study at this link: The Efficacy of Selective Serotonin Reuptake Inhibitors for the Management of Chronic Pain

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