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When the “amplitude of pulsation” in the migraine arteries comes down, the pain of migraine comes down at the same, or very similar rate.  This is not a medical “opinion”, it’s a measurable repeatable verifiable scientific fact. Here’s how we measure that and prove it:

Certain migraine medications are not pain killers at all but are “vaso-constrictors.” This means that they  cause the diameter of “migraine arteries” to reduce.

This can be easily and reliably measured because the migraine arteries are just under the scalp, very close to the surface of the skin. The measurements are so easy to perform that more than half of all migraine sufferers have detected problems in these arteries with their fingers before ever having them examined by a specialist. Sufferers  often press on these arteries to relieve pain.

The measurements reported on in this paper are that when the arteries become narrower as a result of vaso-constrictor medications, the power of each pulse through the arteries comes down. In other words these vaso-constrictor medications cause the force of each pulse through the arteries to decline.

The power of each pulse is generally referred to as the “amplitude of pulsation”. Scientifically speaking this means the wave height of each pulse.

When the amplitude of pulsation in the migraine arteries comes down, the pain comes down at the same, or very similar rate.

This is a review article  co-authored by Prof E.H. Spierings, Harvard Medical School Department of Neurology.

View the original migraine headache and arteries study at this link: Role of the Extracranial Arteries in Migraine Headache: A Review

Interesting references on the migraine arteries involvement

Small blood vessels in migraine

Arterial responses during migraine  headache 

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